Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders

PTEN is a lipid and protein phosphatase that regulates a diverse range of cellular mechanisms. PTEN is mainly present in the cytosol and transiently associates with the plasma membrane to dephosphorylate PI(3,4,5)P3, thereby antagonizing the PI3-Kinase signaling pathway. Recently, PTEN has been show...

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Detalles Bibliográficos
Autores principales: Kreis, Patricia, Leondaritis, George, Lieberam, Ivo, Eickholt, Britta J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978343/
https://www.ncbi.nlm.nih.gov/pubmed/24744697
http://dx.doi.org/10.3389/fnmol.2014.00023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978343/
https://www.ncbi.nlm.nih.gov/pubmed/24744697
http://dx.doi.org/10.3389/fnmol.2014.00023

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