Cholesterol accumulation caused by low density lipoprotein receptor deficiency or a cholesterol-rich diet results in ectopic bone formation during experimental osteoarthritis

INTRODUCTION: Osteoarthritis (OA) is associated with the metabolic syndrome, however the underlying mechanisms remain unclear. We investigated whether low density lipoprotein (LDL) accumulation leads to increased LDL uptake by synovial macrophages and affects synovial activation, cartilage destructi...

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Detalles Bibliográficos
Autores principales: de Munter, Wouter, Blom, Arjen B, Helsen, Monique M, Walgreen, Birgitte, van der Kraan, Peter M, Joosten, Leo AB, van den Berg, Wim B, van Lent, Peter LEM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978425/
https://www.ncbi.nlm.nih.gov/pubmed/24286458
http://dx.doi.org/10.1186/ar4367

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978425/
https://www.ncbi.nlm.nih.gov/pubmed/24286458
http://dx.doi.org/10.1186/ar4367

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