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C/EBP homologous protein drives pro-catabolic responses in chondrocytes

INTRODUCTION: Excess C/EBP homologous protein (CHOP) expression is one feature of the unfolded protein response (UPR) to endoplasmic reticulum (ER) stress. Here, we focused on CHOP expression and function in chondrocytes. METHODS: We studied human knee osteoarthritis (OA) cartilage, bovine chondrocy...

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Detalles Bibliográficos
Autores principales: Husa, Matt, Petursson, Freyr, Lotz, Martin, Terkeltaub, Robert, Liu-Bryan, Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978428/
https://www.ncbi.nlm.nih.gov/pubmed/24351550
http://dx.doi.org/10.1186/ar4415