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Cancer mutation signatures, DNA damage mechanisms, and potential clinical implications

Knowledge of cancer genomic DNA sequences has created unprecedented opportunities for mutation studies. Computational analyses have begun to decipher mutational signatures that identify underlying causes. A recent analysis encompassing 30 cancer types reported 20 distinct mutation signatures, result...

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Detalles Bibliográficos
Autor principal: Harris, Reuben S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978439/
https://www.ncbi.nlm.nih.gov/pubmed/24073723
http://dx.doi.org/10.1186/gm490