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Cancer mutation signatures, DNA damage mechanisms, and potential clinical implications
Knowledge of cancer genomic DNA sequences has created unprecedented opportunities for mutation studies. Computational analyses have begun to decipher mutational signatures that identify underlying causes. A recent analysis encompassing 30 cancer types reported 20 distinct mutation signatures, result...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978439/ https://www.ncbi.nlm.nih.gov/pubmed/24073723 http://dx.doi.org/10.1186/gm490 |