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miR-31 controls osteoclast formation and bone resorption by targeting RhoA

INTRODUCTION: Increased activity of osteoclasts is responsible for bone loss and joint destruction in rheumatoid arthritis. For osteoclast development and bone resorption activity, cytoskeletal organization must be properly regulated. MicroRNAs (miRNAs) are endogenous small noncoding RNAs that suppr...

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Detalles Bibliográficos
Autores principales: Mizoguchi, Fumitaka, Murakami, Yousuke, Saito, Tetsuya, Miyasaka, Nobuyuki, Kohsaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978447/
https://www.ncbi.nlm.nih.gov/pubmed/24004633
http://dx.doi.org/10.1186/ar4282