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A simple consensus approach improves somatic mutation prediction accuracy

Differentiating true somatic mutations from artifacts in massively parallel sequencing data is an immense challenge. To develop methods for optimal somatic mutation detection and to identify factors influencing somatic mutation prediction accuracy, we validated predictions from three somatic mutatio...

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Detalles Bibliográficos
Autores principales: Goode, David L, Hunter, Sally M, Doyle, Maria A, Ma, Tao, Rowley, Simone M, Choong, David, Ryland, Georgina L, Campbell, Ian G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978449/
https://www.ncbi.nlm.nih.gov/pubmed/24073752
http://dx.doi.org/10.1186/gm494