Cargando…

Clinicopathologic assessment and imaging of tauopathies in neurodegenerative dementias

Microtubule-associated protein tau encoded by the MAPT gene binds to microtubules and is important for maintaining neuronal morphology and function. Alternative splicing of MAPT pre-mRNA generates six major tau isoforms in the adult central nervous system resulting in tau proteins with three or four...

Descripción completa

Detalles Bibliográficos
Autores principales: Murray, Melissa E, Kouri, Naomi, Lin, Wen-Lang, Jack, Clifford R, Dickson, Dennis W, Vemuri, Prashanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978456/
https://www.ncbi.nlm.nih.gov/pubmed/24382028
http://dx.doi.org/10.1186/alzrt231