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Interplay of choline metabolites and genes in patient-derived breast cancer xenografts

INTRODUCTION: Dysregulated choline metabolism is a well-known feature of breast cancer, but the underlying mechanisms are not fully understood. In this study, the metabolomic and transcriptomic characteristics of a large panel of human breast cancer xenograft models were mapped, with focus on cholin...

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Detalles Bibliográficos
Autores principales: Grinde, Maria T, Skrbo, Nirma, Moestue, Siver A, Rødland, Einar A, Borgan, Eldrid, Kristian, Alexandr, Sitter, Beathe, Bathen, Tone F, Børresen-Dale, Anne-Lise, Mælandsmo, Gunhild M, Engebraaten, Olav, Sørlie, Therese, Marangoni, Elisabetta, Gribbestad, Ingrid S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978476/
https://www.ncbi.nlm.nih.gov/pubmed/24447408
http://dx.doi.org/10.1186/bcr3597