Synthesis and Preliminary Evaluation of a 2-Oxoquinoline Carboxylic Acid Derivative for PET Imaging the Cannabinoid Type 2 Receptor

Cannabinoid receptor subtype 2 (CB2) has been shown to be up-regulated in activated microglia and therefore plays an important role in neuroinflammatory and neurodegenerative diseases such as multiple sclerosis, amyotrophic lateral sclerosis and Alzheimer’s disease. The CB2 receptor is therefore con...

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Detalles Bibliográficos
Autores principales: Mu, Linjing, Slavik, Roger, Müller, Adrienne, Popaj, Kasim, Čermak, Stjepko, Weber, Markus, Schibli, Roger, Krämer, Stefanie D., Ametamey, Simon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978495/
https://www.ncbi.nlm.nih.gov/pubmed/24662272
http://dx.doi.org/10.3390/ph7030339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978495/
https://www.ncbi.nlm.nih.gov/pubmed/24662272
http://dx.doi.org/10.3390/ph7030339

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