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Lessons and Implications from Genome-Wide Association Studies (GWAS) Findings of Blood Cell Phenotypes

Genome-wide association studies (GWAS) have identified reproducible genetic associations with hundreds of human diseases and traits. The vast majority of these associated single nucleotide polymorphisms (SNPs) are non-coding, highlighting the challenge in moving from genetic findings to mechanistic...

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Detalles Bibliográficos
Autores principales: Chami, Nathalie, Lettre, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978511/
https://www.ncbi.nlm.nih.gov/pubmed/24705286
http://dx.doi.org/10.3390/genes5010051