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Lessons from Genome-Wide Search for Disease-Related Genes with Special Reference to HLA-Disease Associations
The relationships between diseases and genetic factors are by no means uniform. Single-gene diseases are caused primarily by rare mutations of specific genes. Although each single-gene disease has a low prevalence, there are an estimated 5000 or more such diseases in the world. In contrast, multifac...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978513/ https://www.ncbi.nlm.nih.gov/pubmed/24705288 http://dx.doi.org/10.3390/genes5010084 |