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Molecular Mechanisms of DNA Replication Checkpoint Activation

The major challenge of the cell cycle is to deliver an intact, and fully duplicated, genetic material to the daughter cells. To this end, progression of DNA synthesis is monitored by a feedback mechanism known as replication checkpoint that is untimely linked to DNA replication. This signaling pathw...

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Detalles Bibliográficos
Autores principales: Recolin, Bénédicte, van der Laan, Siem, Tsanov, Nikolay, Maiorano, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978517/
https://www.ncbi.nlm.nih.gov/pubmed/24705291
http://dx.doi.org/10.3390/genes5010147