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Application of Pharmacokinetic and Pharmacodynamic Analysis to the Development of Liposomal Formulations for Oncology

Liposomal formulations of anticancer agents have been developed to prolong drug circulating lifetime, enhance anti-tumor efficacy by increasing tumor drug deposition, and reduce drug toxicity by avoiding critical normal tissues. Despite the clinical approval of numerous liposome-based chemotherapeut...

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Detalles Bibliográficos
Autores principales:	Ait-Oudhia, Sihem, Mager, Donald E., Straubinger, Robert M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978529/ https://www.ncbi.nlm.nih.gov/pubmed/24647104 http://dx.doi.org/10.3390/pharmaceutics6010137

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