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β1-integrin via NF-κB signaling is essential for acquisition of invasiveness in a model of radiation treated in situ breast cancer

INTRODUCTION: Ductal carcinoma in situ (DCIS) is characterized by non-invasive cancerous cell growth within the breast ducts. Although radiotherapy is commonly used in the treatment of DCIS, the effect and molecular mechanism of ionizing radiation (IR) on DCIS are not well understood, and invasive r...

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Detalles Bibliográficos
Autores principales: Nam, Jin-Min, Ahmed, Kazi M, Costes, Sylvain, Zhang, Hui, Onodera, Yasuhito, Olshen, Adam B, Hatanaka, Kanako C, Kinoshita, Rumiko, Ishikawa, Masayori, Sabe, Hisataka, Shirato, Hiroki, Park, Catherine C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978561/
https://www.ncbi.nlm.nih.gov/pubmed/23883667
http://dx.doi.org/10.1186/bcr3454