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The progressive ankylosis gene product ANK regulates extracellular ATP levels in primary articular chondrocytes

INTRODUCTION: Extracellular ATP (eATP) is released by articular chondrocytes under physiological and pathological conditions. High eATP levels cause pathologic calcification, damage cartilage, and mediate pain. We recently showed that stable over-expression of the progressive ankylosis gene product,...

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Detalles Bibliográficos
Autores principales: Rosenthal, Ann K, Gohr, Claudia M, Mitton-Fitzgerald, Elizabeth, Lutz, Megan K, Dubyak, George R, Ryan, Lawrence M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978574/
https://www.ncbi.nlm.nih.gov/pubmed/24286344
http://dx.doi.org/10.1186/ar4337