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Decreased expression of the endothelial cell-derived factor EGFL7 in systemic sclerosis: potential contribution to impaired angiogenesis and vasculogenesis

INTRODUCTION: Microvascular damage and defective angiogenesis and vasculogenesis have a major role in the pathogenesis of systemic sclerosis (SSc). Epidermal growth factor-like domain 7 (EGFL7) is a proangiogenic molecule which is predominantly expressed and secreted by endothelial cells and their p...

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Detalles Bibliográficos
Autores principales: Manetti, Mirko, Guiducci, Serena, Romano, Eloisa, Avouac, Jérôme, Rosa, Irene, Ruiz, Barbara, Lepri, Gemma, Bellando-Randone, Silvia, Ibba-Manneschi, Lidia, Allanore, Yannick, Matucci-Cerinic, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978601/
https://www.ncbi.nlm.nih.gov/pubmed/24286167
http://dx.doi.org/10.1186/ar4349