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Single cell expression quantitative trait loci and complex traits

The recently developed ability to quantify mRNA abundance and noise in single cells has allowed the effect of heritable variations on gene function to be re-evaluated. A recent study has shown that major sources of variation are masked when gene expression is averaged over many cells. Heritable vari...

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Detalles Bibliográficos
Autor principal: Petretto, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978606/
https://www.ncbi.nlm.nih.gov/pubmed/23998908
http://dx.doi.org/10.1186/gm476