Clinical development of mTOR inhibitors in breast cancer

The mammalian target of rapamycin (mTOR) pathway is a central pathway that regulates mRNA translation, protein synthesis, glucose metabolism, lipid synthesis and autophagy, and is involved in malignant transformation. Several randomized trials have shown that the use of mTOR inhibitors could improve...

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Detalles Bibliográficos
Autores principales: Vicier, Cecile, Dieci, Maria Vittoria, Arnedos, Monica, Delaloge, Suzette, Viens, Patrice, Andre, Fabrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978635/
https://www.ncbi.nlm.nih.gov/pubmed/25189767
http://dx.doi.org/10.1186/bcr3618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978635/
https://www.ncbi.nlm.nih.gov/pubmed/25189767
http://dx.doi.org/10.1186/bcr3618

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