Induction of nerve growth factor expression and release by mechanical and inflammatory stimuli in chondrocytes: possible involvement in osteoarthritis pain

INTRODUCTION: Nerve growth factor (NGF) level is increased in osteoarthritis (OA) joints and is involved in pain associated with OA. Stimuli responsible for NGF stimulation in chondrocytes are unknown. We investigated whether mechanical stress and proinflammatory cytokines may influence NGF synthesi...

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Detalles Bibliográficos
Autores principales: Pecchi, Emilie, Priam, Sabrina, Gosset, Marjolaine, Pigenet, Audrey, Sudre, Laure, Laiguillon, Marie-Charlotte, Berenbaum, Francis, Houard, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978639/
https://www.ncbi.nlm.nih.gov/pubmed/24438745
http://dx.doi.org/10.1186/ar4443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978639/
https://www.ncbi.nlm.nih.gov/pubmed/24438745
http://dx.doi.org/10.1186/ar4443

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