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Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase

Bulk degradation of cytoplasmic material is mediated by a highly conserved intracellular trafficking pathway termed autophagy. This pathway is characterized by the formation of double-membrane vesicles termed autophagosomes engulfing the substrate and transporting it to the vacuole/lysosome for brea...

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Detalles Bibliográficos
Autores principales: Papinski, Daniel, Schuschnig, Martina, Reiter, Wolfgang, Wilhelm, Larissa, Barnes, Christopher A., Maiolica, Alessio, Hansmann, Isabella, Pfaffenwimmer, Thaddaeus, Kijanska, Monika, Stoffel, Ingrid, Lee, Sung Sik, Brezovich, Andrea, Lou, Jane Hua, Turk, Benjamin E., Aebersold, Ruedi, Ammerer, Gustav, Peter, Matthias, Kraft, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978657/
https://www.ncbi.nlm.nih.gov/pubmed/24440502
http://dx.doi.org/10.1016/j.molcel.2013.12.011