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Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase
Bulk degradation of cytoplasmic material is mediated by a highly conserved intracellular trafficking pathway termed autophagy. This pathway is characterized by the formation of double-membrane vesicles termed autophagosomes engulfing the substrate and transporting it to the vacuole/lysosome for brea...
Autores principales: | Papinski, Daniel, Schuschnig, Martina, Reiter, Wolfgang, Wilhelm, Larissa, Barnes, Christopher A., Maiolica, Alessio, Hansmann, Isabella, Pfaffenwimmer, Thaddaeus, Kijanska, Monika, Stoffel, Ingrid, Lee, Sung Sik, Brezovich, Andrea, Lou, Jane Hua, Turk, Benjamin E., Aebersold, Ruedi, Ammerer, Gustav, Peter, Matthias, Kraft, Claudine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978657/ https://www.ncbi.nlm.nih.gov/pubmed/24440502 http://dx.doi.org/10.1016/j.molcel.2013.12.011 |
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