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Cardiac contractility modulation increases action potential duration dispersion and decreases ventricular fibrillation threshold via β1-adrenoceptor activation in the crystalloid perfused normal rabbit heart()()

BACKGROUND/OBJECTIVES: Cardiac contractility modulation (CCM) is a new treatment being developed for heart failure (HF) involving application of electrical current during the absolute refractory period. We have previously shown that CCM increases ventricular force through β1-adrenoceptor activation...

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Detalles Bibliográficos
Autores principales: Winter, James, Brack, Kieran E., Coote, John H., Ng, G. André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978661/
https://www.ncbi.nlm.nih.gov/pubmed/24456882
http://dx.doi.org/10.1016/j.ijcard.2013.12.184