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Double-antiangiogenic protein DAAP targeting vascular endothelial growth factor A and angiopoietins attenuates collagen-induced arthritis

INTRODUCTION: Angiogenesis plays a critical role in synovial inflammation and joint destruction in rheumatoid arthritis (RA). Vascular endothelial growth factor A (VEGF-A) and angiopoietins are two important mediators of synovial angiogenesis. We have previously developed a novel chimeric decoy rece...

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Detalles Bibliográficos
Autores principales: Hah, Young-Sool, Koh, Young Jun, Lim, Hye Song, Kim, Hyun-Ok, Cheon, Yun-Hong, Noh, Hae Sook, Jang, Kyu Yun, Lee, Sang Yong, Lee, Gyun Min, Koh, Gou Young, Lee, Sang-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978684/
https://www.ncbi.nlm.nih.gov/pubmed/23945080
http://dx.doi.org/10.1186/ar4265