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IL-29 enhances Toll-like receptor-mediated IL-6 and IL-8 production by the synovial fibroblasts from rheumatoid arthritis patients

INTRODUCTION: We previously reported that IL-29, a newly described member of interferon (IFN) family, was overexpressed in blood and synovium of rheumatoid arthritis (RA) patients and triggered proinflammatory cytokine IL-6 and IL-8 mRNA expression in RA synovial fibroblasts (RA-FLS). This suggests...

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Detalles Bibliográficos
Autores principales: Xu, Lingxiao, Feng, Xiaoke, Tan, Wenfeng, Gu, Weijuan, Guo, Dunming, Zhang, Miaojia, Wang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978693/
https://www.ncbi.nlm.nih.gov/pubmed/24286242
http://dx.doi.org/10.1186/ar4357