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Fucosyltransferase 1 mediates angiogenesis, cell adhesion and rheumatoid arthritis synovial tissue fibroblast proliferation

INTRODUCTION: We previously reported that sialyl Lewis(y), synthesized by fucosyltransferases, is involved in angiogenesis. Fucosyltransferase 1 (fut1) is an α(1,2)-fucosyltransferase responsible for synthesis of the H blood group and Lewis(y) antigens. However, the angiogenic involvement of fut 1 i...

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Detalles Bibliográficos
Autores principales: Isozaki, Takeo, Ruth, Jeffrey H, Amin, Mohammad A, Campbell, Phillip L, Tsou, Pei-Suen, Ha, Christine M, Haines, G Kenneth, Edhayan, Gautam, Koch, Alisa E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978694/
https://www.ncbi.nlm.nih.gov/pubmed/24467809
http://dx.doi.org/10.1186/ar4456