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Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells

Breast cancer stem-like cells (CSCs) are an important therapeutic target as they are purported to be responsible for tumor initiation, maintenance, metastases, and disease recurrence. Interleukin-8 (IL-8) is upregulated in breast cancer compared with normal breast tissue and is associated with poor...

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Detalles Bibliográficos
Autores principales: Singh, Jagdeep K, Simões, Bruno M, Howell, Sacha J, Farnie, Gillian, Clarke, Robert B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978717/
https://www.ncbi.nlm.nih.gov/pubmed/24041156
http://dx.doi.org/10.1186/bcr3436