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Amyloid β-protein oligomers and Alzheimer’s disease

The oligomer cascade hypothesis, which states that oligomers are the initiating pathologic agents in Alzheimer’s disease, has all but supplanted the amyloid cascade hypothesis, which suggested that fibers were the key etiologic agents in Alzheimer’s disease. We review here the results of in vivo, in...

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Detalles Bibliográficos
Autores principales: Hayden, Eric Y, Teplow, David B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978746/
https://www.ncbi.nlm.nih.gov/pubmed/24289820
http://dx.doi.org/10.1186/alzrt226