Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

INTRODUCTION: Signal transducers and activators of transcription 3 (STAT3) signaling is constitutively activated in various cancers including breast cancer and has emerged as a novel potential anti-cancer target. STAT3 has been demonstrated to be a target of sorafenib, and a protein tyrosine phospha...

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Detalles Bibliográficos
Autores principales: Liu, Chun-Yu, Tseng, Ling-Ming, Su, Jung-Chen, Chang, Kung-Chi, Chu, Pei-Yi, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978748/
https://www.ncbi.nlm.nih.gov/pubmed/23938089
http://dx.doi.org/10.1186/bcr3457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978748/
https://www.ncbi.nlm.nih.gov/pubmed/23938089
http://dx.doi.org/10.1186/bcr3457

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