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The immunogenicity to the first anti-TNF therapy determines the outcome of switching to a second anti-TNF therapy in spondyloarthritis patients

INTRODUCTION: Anti-TNF drugs have proven to be effective against spondyloarthritis (SpA), although 30% of patients fail to respond or experience adverse events leading to treatment discontinuation. In rheumatoid arthritis, the presence of anti-drug antibodies (ADA) against the first TNF inhibitor in...

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Detalles Bibliográficos
Autores principales: Plasencia, Chamaida, Pascual-Salcedo, Dora, García-Carazo, Sara, Lojo, Leticia, Nuño, Laura, Villalba, Alejandro, Peiteado, Diana, Arribas, Florencia, Díez, Jesus, López-Casla, Maria Teresa, Martín-Mola, Emilio, Balsa, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978754/
https://www.ncbi.nlm.nih.gov/pubmed/23890223
http://dx.doi.org/10.1186/ar4258