Encounter complexes and dimensionality reduction in protein–protein association

An outstanding challenge has been to understand the mechanism whereby proteins associate. We report here the results of exhaustively sampling the conformational space in protein–protein association using a physics-based energy function. The agreement between experimental intermolecular paramagnetic...

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Detalles Bibliográficos
Autores principales: Kozakov, Dima, Li, Keyong, Hall, David R, Beglov, Dmitri, Zheng, Jiefu, Vakili, Pirooz, Schueler-Furman, Ora, Paschalidis, Ioannis Ch, Clore, G Marius, Vajda, Sandor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978769/
https://www.ncbi.nlm.nih.gov/pubmed/24714491
http://dx.doi.org/10.7554/eLife.01370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978769/
https://www.ncbi.nlm.nih.gov/pubmed/24714491
http://dx.doi.org/10.7554/eLife.01370

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