Propagation of tau pathology in Alzheimer’s disease: identification of novel therapeutic targets

Accumulation and aggregation of the microtubule-associated protein tau are a pathological hallmark of neurodegenerative disorders such as Alzheimer’s disease (AD). In AD, tau becomes abnormally phosphorylated and forms inclusions throughout the brain, starting in the entorhinal cortex and progressiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Pooler, Amy M, Polydoro, Manuela, Wegmann, Susanne, Nicholls, Samantha B, Spires-Jones, Tara L, Hyman, Bradley T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978816/
https://www.ncbi.nlm.nih.gov/pubmed/24152385
http://dx.doi.org/10.1186/alzrt214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978816/
https://www.ncbi.nlm.nih.gov/pubmed/24152385
http://dx.doi.org/10.1186/alzrt214

Ejemplares similares