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Regeneration of the aged thymus by a single transcription factor

Thymic involution is central to the decline in immune system function that occurs with age. By regenerating the thymus, it may therefore be possible to improve the ability of the aged immune system to respond to novel antigens. Recently, diminished expression of the thymic epithelial cell (TEC)-spec...

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Detalles Bibliográficos
Autores principales: Bredenkamp, Nicholas, Nowell, Craig S., Blackburn, C. Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978836/
https://www.ncbi.nlm.nih.gov/pubmed/24715454
http://dx.doi.org/10.1242/dev.103614