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Regeneration of the aged thymus by a single transcription factor
Thymic involution is central to the decline in immune system function that occurs with age. By regenerating the thymus, it may therefore be possible to improve the ability of the aged immune system to respond to novel antigens. Recently, diminished expression of the thymic epithelial cell (TEC)-spec...
Autores principales: | Bredenkamp, Nicholas, Nowell, Craig S., Blackburn, C. Clare |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978836/ https://www.ncbi.nlm.nih.gov/pubmed/24715454 http://dx.doi.org/10.1242/dev.103614 |
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