Efficiency of whole genome amplification of single circulating tumor cells enriched by CellSearch and sorted by FACS

BACKGROUND: Tumor cells in the blood of patients with metastatic carcinomas are associated with poor survival. Knowledge of the cells’ genetic make-up can help to guide targeted therapy. We evaluated the efficiency and quality of isolation and amplification of DNA from single circulating tumor cells...

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Detalles Bibliográficos
Autores principales: Swennenhuis, Joost F, Reumers, Joke, Thys, Kim, Aerssens, Jeroen, Terstappen, Leon WMM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978840/
https://www.ncbi.nlm.nih.gov/pubmed/24286536
http://dx.doi.org/10.1186/gm510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978840/
https://www.ncbi.nlm.nih.gov/pubmed/24286536
http://dx.doi.org/10.1186/gm510

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