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Efficiency of whole genome amplification of single circulating tumor cells enriched by CellSearch and sorted by FACS
BACKGROUND: Tumor cells in the blood of patients with metastatic carcinomas are associated with poor survival. Knowledge of the cells’ genetic make-up can help to guide targeted therapy. We evaluated the efficiency and quality of isolation and amplification of DNA from single circulating tumor cells...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978840/ https://www.ncbi.nlm.nih.gov/pubmed/24286536 http://dx.doi.org/10.1186/gm510 |