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Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity?

Paracrine signaling mechanisms play a critical role in both normal mammary gland development and breast cancer. Dissection of these mechanisms using genetically engineered mouse models has provided significant insight into our understanding of the mechanisms that guide intratumoral heterogeneity. In...

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Detalles Bibliográficos
Autores principales: Rosen, Jeffrey M, Roarty, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978850/
https://www.ncbi.nlm.nih.gov/pubmed/24476463
http://dx.doi.org/10.1186/bcr3610