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Analysis of epigenetic changes in survivors of preterm birth reveals the effect of gestational age and evidence for a long term legacy

BACKGROUND: Preterm birth confers a high risk of adverse long term health outcomes for survivors, yet the underlying molecular mechanisms are unclear. We hypothesized that effects of preterm birth can be mediated through measurable epigenomic changes throughout development. We therefore used a longi...

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Detalles Bibliográficos
Autores principales: Cruickshank, Mark N, Oshlack, Alicia, Theda, Christiane, Davis, Peter G, Martino, David, Sheehan, Penelope, Dai, Yun, Saffery, Richard, Doyle, Lex W, Craig, Jeffrey M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978871/
https://www.ncbi.nlm.nih.gov/pubmed/24134860
http://dx.doi.org/10.1186/gm500