Cargando…

Nonhypoxic regulation and role of hypoxia-inducible factor 1 in aromatase inhibitor resistant breast cancer

INTRODUCTION: Although aromatase inhibitors (AIs; for example, letrozole) are highly effective in treating estrogen receptor positive (ER+) breast cancer, a significant percentage of patients either do not respond to AIs or become resistant to them. Previous studies suggest that acquired resistance...

Descripción completa

Detalles Bibliográficos
Autores principales: Kazi, Armina A, Gilani, Rabia A, Schech, Amanda J, Chumsri, Saranya, Sabnis, Gauri, Shah, Preeti, Goloubeva, Olga, Kronsberg, Shari, Brodie, Angela H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978891/
https://www.ncbi.nlm.nih.gov/pubmed/24472707
http://dx.doi.org/10.1186/bcr3609