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Natural breaking of the maternal silence at the mouse and human imprinted Prader-Willi locus: A whisper with functional consequences
Genomic imprinting is a normal process of epigenetic regulation leading some autosomal genes to be expressed from one parental allele only, the other parental allele being silenced. The reasons why this mechanism has been selected throughout evolution are not clear; however, expression dosage is cri...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978896/ https://www.ncbi.nlm.nih.gov/pubmed/25003016 http://dx.doi.org/10.4161/rdis.27228 |