Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

INTRODUCTION: The ability to degrade neutrophil extracellular traps (NETs) is reduced in a subset of patients with systemic lupus erythematosus (SLE). NETs consist of chromatin covered with antimicrobial enzymes and are normally degraded by DNase-I, an enzyme which is known to have reduced activity...

Descripción completa

Detalles Bibliográficos
Autores principales: Leffler, Jonatan, Gullstrand, Birgitta, Jönsen, Andreas, Nilsson, Jan-Åke, Martin, Myriam, Blom, Anna M, Bengtsson, Anders A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978901/
https://www.ncbi.nlm.nih.gov/pubmed/23945056
http://dx.doi.org/10.1186/ar4264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978901/
https://www.ncbi.nlm.nih.gov/pubmed/23945056
http://dx.doi.org/10.1186/ar4264

Ejemplares similares