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Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

INTRODUCTION: The ability to degrade neutrophil extracellular traps (NETs) is reduced in a subset of patients with systemic lupus erythematosus (SLE). NETs consist of chromatin covered with antimicrobial enzymes and are normally degraded by DNase-I, an enzyme which is known to have reduced activity...

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Detalles Bibliográficos
Autores principales:	Leffler, Jonatan, Gullstrand, Birgitta, Jönsen, Andreas, Nilsson, Jan-Åke, Martin, Myriam, Blom, Anna M, Bengtsson, Anders A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978901/ https://www.ncbi.nlm.nih.gov/pubmed/23945056 http://dx.doi.org/10.1186/ar4264

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