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Identification of three new cis-regulatory IRF5 polymorphisms: in vitro studies

BACKGROUND: Polymorphisms in the interferon regulatory factor 5 (IRF5) gene are associated with susceptibility to systemic lupus erythematosus, rheumatoid arthritis and other diseases through independent risk and protective haplotypes. Several functional polymorphisms are already known, but they do...

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Detalles Bibliográficos
Autores principales: Alonso-Perez, Elisa, Fernandez-Poceiro, Romina, Lalonde, Emilie, Kwan, Tony, Calaza, Manuel, Gomez-Reino, Juan J, Majewski, Jacek, Gonzalez, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978921/
https://www.ncbi.nlm.nih.gov/pubmed/23941291
http://dx.doi.org/10.1186/ar4262