Circulating levels of soluble MER in lupus reflect M2c activation of monocytes/macrophages, autoantibody specificities and disease activity

INTRODUCTION: Systemic lupus erythematosus (SLE) is characterized by impaired efferocytosis and aberrant activation of innate immunity. We asked if shedding of MER receptor tyrosine kinase (MerTK) and AXL into soluble (s) ectodomains was related to immunological and clinical aspects of SLE. METHODS:...

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Detalles Bibliográficos
Autores principales: Zizzo, Gaetano, Guerrieri, Justus, Dittman, Lindsay M, Merrill, Joan T, Cohen, Philip L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978923/
https://www.ncbi.nlm.nih.gov/pubmed/24325951
http://dx.doi.org/10.1186/ar4407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978923/
https://www.ncbi.nlm.nih.gov/pubmed/24325951
http://dx.doi.org/10.1186/ar4407

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