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Notch activation stimulates migration of breast cancer cells and promotes tumor growth

INTRODUCTION: Dysregulated NOTCH receptor activity has been implicated in breast cancer but the mechanisms by which NOTCH contributes to transformation are not yet clear, as it has context-dependent effects on the properties of transformed cells. METHODS: We have used various in vitro and in vivo ca...

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Detalles Bibliográficos
Autores principales: Bolós, Victoria, Mira, Emilia, Martínez-Poveda, Beatriz, Luxán, Guillermo, Cañamero, Marta, Martínez-A, Carlos, Mañes, Santos, de la Pompa, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978930/
https://www.ncbi.nlm.nih.gov/pubmed/23826634
http://dx.doi.org/10.1186/bcr3447