Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1β

INTRODUCTION: Arthritic diseases are characterized by the degradation of collagenous and noncollagenous extracellular matrix (ECM) components in articular cartilage. The increased expression and activity of matrix metalloproteinases (MMPs) is partly responsible for cartilage degradation. This study...

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Detalles Bibliográficos
Autores principales: Williams, Adam, Smith, Julia R, Allaway, David, Harris, Pat, Liddell, Susan, Mobasheri, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978949/
https://www.ncbi.nlm.nih.gov/pubmed/24373218
http://dx.doi.org/10.1186/ar4424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978949/
https://www.ncbi.nlm.nih.gov/pubmed/24373218
http://dx.doi.org/10.1186/ar4424

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