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Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes

INTRODUCTION: Inflammatory cytokines play a key role in the pathogenesis of joint diseases such as rheumatoid arthritis (RA). Current therapies target mainly tumor necrosis factor α (TNF-α) as this has proven benefits. However, a large number of patients do not respond to or become resistant to anti...

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Detalles Bibliográficos
Autores principales: Buhrmann, Constanze, Shayan, Parviz, Aggarwal, Bharat B, Shakibaei, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979010/
https://www.ncbi.nlm.nih.gov/pubmed/24283517
http://dx.doi.org/10.1186/ar4393