Cargando…

Evidence that TNF-β (lymphotoxin α) can activate the inflammatory environment in human chondrocytes

INTRODUCTION: Inflammatory cytokines play a key role in the pathogenesis of joint diseases such as rheumatoid arthritis (RA). Current therapies target mainly tumor necrosis factor α (TNF-α) as this has proven benefits. However, a large number of patients do not respond to or become resistant to anti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buhrmann, Constanze, Shayan, Parviz, Aggarwal, Bharat B, Shakibaei, Mehdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979010/ https://www.ncbi.nlm.nih.gov/pubmed/24283517 http://dx.doi.org/10.1186/ar4393

Ejemplares similares

Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α
por: Buhrmann, Constanze, et al.
Publicado: (2017)

Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol
por: Buhrmann, Constanze, et al.
Publicado: (2019)

Calebin A Potentiates the Effect of 5-FU and TNF-β (Lymphotoxin α) against Human Colorectal Cancer Cells: Potential Role of NF-κB †
por: Buhrmann, Constanze, et al.
Publicado: (2020)

Evidence That Calebin A, a Component of Curcuma Longa Suppresses NF-κB Mediated Proliferation, Invasion and Metastasis of Human Colorectal Cancer Induced by TNF-β (Lymphotoxin)
por: Buhrmann, Constanze, et al.
Publicado: (2019)

Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells
por: Buhrmann, Constanze, et al.
Publicado: (2018)

Curcumin Attenuates Environment-Derived Osteoarthritis by Sox9/NF-kB Signaling Axis
por: Buhrmann, Constanze, et al.
Publicado: (2021)

Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules
por: Buhrmann, Constanze, et al.
Publicado: (2017)

Resveratrol Suppresses Cross-Talk between Colorectal Cancer Cells and Stromal Cells in Multicellular Tumor Microenvironment: A Bridge between In Vitro and In Vivo Tumor Microenvironment Study
por: Buhrmann, Constanze, et al.
Publicado: (2020)

Resveratrol induces apoptosis by modulating the reciprocal crosstalk between p53 and Sirt-1 in the CRC tumor microenvironment
por: Brockmueller, Aranka, et al.
Publicado: (2023)

Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells
por: Buhrmann, Constanze, et al.
Publicado: (2016)

Curcumin Suppresses Crosstalk between Colon Cancer Stem Cells and Stromal Fibroblasts in the Tumor Microenvironment: Potential Role of EMT
por: Buhrmann, Constanze, et al.
Publicado: (2014)

Curcumin Chemosensitizes 5-Fluorouracil Resistant MMR-Deficient Human Colon Cancer Cells in High Density Cultures
por: Shakibaei, Mehdi, et al.
Publicado: (2014)

Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer
por: Shakibaei, Mehdi, et al.
Publicado: (2015)

Evidence That Tumor Microenvironment Initiates Epithelial-To-Mesenchymal Transition and Calebin A can Suppress it in Colorectal Cancer Cells
por: Buhrmann, Constanze, et al.
Publicado: (2021)

Resveratrol Mediated Modulation of Sirt-1/Runx2 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells: Potential Role of Runx2 Deacetylation
por: Shakibaei, Mehdi, et al.
Publicado: (2012)

Elevated lymphotoxin-α (TNFβ) is associated with intervertebral disc degeneration
por: Guo, Zhu, et al.
Publicado: (2021)

Targeting NF-κB Signaling by Calebin A, a Compound of Turmeric, in Multicellular Tumor Microenvironment: Potential Role of Apoptosis Induction in CRC Cells
por: Buhrmann, Constanze, et al.
Publicado: (2020)

Evidence That β1-Integrin Is Required for the Anti-Viability and Anti-Proliferative Effect of Resveratrol in CRC Cells
por: Brockmueller, Aranka, et al.
Publicado: (2022)

Resveratrol-mediated SIRT-1 Interactions with p300 Modulate Receptor Activator of NF-κB Ligand (RANKL) Activation of NF-κB Signaling and Inhibit Osteoclastogenesis in Bone-derived Cells
por: Shakibaei, Mehdi, et al.
Publicado: (2011)

Multitargeting Effects of Calebin A on Malignancy of CRC Cells in Multicellular Tumor Microenvironment
por: Buhrmann, Constanze, et al.
Publicado: (2021)

Synergistic chondroprotective effects of curcumin and resveratrol in human articular chondrocytes: inhibition of IL-1β-induced NF-κB-mediated inflammation and apoptosis
por: Csaki, Constanze, et al.
Publicado: (2009)

Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment
por: Buhrmann, Constanze, et al.
Publicado: (2010)

Lymphotoxin, but Not TNF, Is Required for Prion Invasion of Lymph Nodes
por: O'Connor, Tracy, et al.
Publicado: (2012)

β1-Integrin plays a major role in resveratrol-mediated anti-invasion effects in the CRC microenvironment
por: Brockmueller, Aranka, et al.
Publicado: (2022)

A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-α/β and TNF-α in cultured endothelial cells
por: Pablos, José L, et al.
Publicado: (2005)

RANKL expression in chondrocytes and its promotion by lymphotoxin-α in the course of cartilage destruction during rheumatoid arthritis
por: Takeshita, Ayumu, et al.
Publicado: (2021)

Bacterial lipopolysaccharides form procollagen-endotoxin complexes that trigger cartilage inflammation and degeneration: implications for the development of rheumatoid arthritis
por: Lorenz, Wolfgang, et al.
Publicado: (2013)

Membrane lymphotoxin-α(2)β is a novel tumor necrosis factor (TNF) receptor 2 (TNFR2) agonist
por: Kucka, Kirstin, et al.
Publicado: (2021)

IGF-1 and PDGF-bb Suppress IL-1β-Induced Cartilage Degradation through Down-Regulation of NF-κB Signaling: Involvement of Src/PI-3K/AKT Pathway
por: Montaseri, Azadeh, et al.
Publicado: (2011)

Multiple roles for tumor necrosis factor-α and lymphotoxin α/β in immunity and autoimmunity
por: McDevitt, Hugh, et al.
Publicado: (2002)

Herbal Remedies as Potential in Cartilage Tissue Engineering: An Overview of New Therapeutic Approaches and Strategies
por: Buhrmann, Constanze, et al.
Publicado: (2020)

Autocrine Tumor Necrosis Factor (TNF) and Lymphotoxin (LT) α Differentially Modulate Cellular Sensitivity to TNF/LT-α Cytotoxicity in L929 Cells
por: Decoster, Els, et al.
Publicado: (1998)

Tumor Necrosis Factor-α and Lymphotoxin-α Mediate Myocardial Ischemic Injury via TNF Receptor 1, but Are Cardioprotective When Activating TNF Receptor 2
por: Zhang, Yanqing, et al.
Publicado: (2013)

Curcumin Modulates Nuclear Factor κB (NF-κB)-mediated Inflammation in Human Tenocytes in Vitro: ROLE OF THE PHOSPHATIDYLINOSITOL 3-KINASE/Akt PATHWAY
por: Buhrmann, Constanze, et al.
Publicado: (2011)

Organophosphorus Compounds and MAPK Signaling Pathways
por: Farkhondeh, Tahereh, et al.
Publicado: (2020)

The Tumor Necrosis Factor Superfamily Members TNFSF14 (LIGHT), Lymphotoxin β and Lymphotoxin β Receptor Interact to Regulate Intestinal Inflammation
por: Giles, Daniel A., et al.
Publicado: (2018)

Neuronal aldosterone elicits a distinct genomic response in pain signaling molecules contributing to inflammatory pain
por: Shaqura, Mohammed, et al.
Publicado: (2020)

A Critical Role of the p75 Tumor Necrosis Factor Receptor (p75TNF-R) in Organ Inflammation Independent of TNF, Lymphotoxin α, or the p55TNF-R
por: Douni, Eleni, et al.
Publicado: (1998)

Secreted Lymphotoxin-α Is Essential for the Control of an Intracellular Bacterial Infection
por: Roach, Daniel R., et al.
Publicado: (2001)

Lymphotoxin α revisited: general features and implications in rheumatoid arthritis
por: Calmon-Hamaty, Flavia, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_br4pmsn42qt2aj7fsrjcsp6jjp