Cargando…

Sequence analysis of T-cell repertoires in health and disease

T-cell antigen receptor (TCR) variability enables the cellular immune system to discriminate between self and non-self. High-throughput TCR sequencing (TCR-seq) involves the use of next generation sequencing platforms to generate large numbers of short DNA sequences covering key regions of the TCR c...

Descripción completa

Detalles Bibliográficos
Autores principales: Woodsworth, Daniel J, Castellarin, Mauro, Holt, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979016/
https://www.ncbi.nlm.nih.gov/pubmed/24172704
http://dx.doi.org/10.1186/gm502