Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy

BACKGROUND: Spinal muscular atrophy (SMA) is a neuromuscular disease resulting from mutations in the survival motor neuron 1 (SMN1) gene. Recent breakthroughs in preclinical research have highlighted several potential novel therapies for SMA, increasing the need for robust and sensitive clinical tri...

Descripción completa

Detalles Bibliográficos
Autores principales: Mutsaers, Chantal A, Lamont, Douglas J, Hunter, Gillian, Wishart, Thomas M, Gillingwater, Thomas H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979019/
https://www.ncbi.nlm.nih.gov/pubmed/24134804
http://dx.doi.org/10.1186/gm498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979019/
https://www.ncbi.nlm.nih.gov/pubmed/24134804
http://dx.doi.org/10.1186/gm498

Ejemplares similares